期刊
CURRENT OPINION IN STRUCTURAL BIOLOGY
卷 19, 期 4, 页码 442-448出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.sbi.2009.04.007
关键词
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资金
- NIH [2RO1 GM066972]
- NSF [CBET-0828724]
The modulation of enzyme function is a key regulatory feature of biological systems. The ability to engineer synthetic enzymes that can be controlled by any arbitrary signal would enable a wide array of sensing applications and therapeutics and provide us with powerful tools for the basic study of biology. Here several recent advances in the engineering of switchable enzymes through domain fusion are discussed.
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