期刊
CURRENT OPINION IN PLANT BIOLOGY
卷 22, 期 -, 页码 56-64出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.pbi.2014.09.004
关键词
-
资金
- NIGMS [R01GM065989]
- DOE [DE-FG02-05er15671]
- NSF [MCB-0718202]
- Direct For Biological Sciences
- Div Of Molecular and Cellular Bioscience [1158054] Funding Source: National Science Foundation
Like electronic circuits, the modular arrangement of cell-signaling networks decides how inputs produce outputs. Animal heterotrimeric guanine nucleotide binding proteins (G-proteins) operate as switches in the circuits that signal between extracellular agonists and intracellular effectors. There still is no biochemical evidence for a receptor or its agonist in the plant G-protein pathways. Plant G-proteins deviate in many important ways from the animal paradigm. This review covers important discoveries from the last two years that enlighten these differences and ends describing alternative wiring diagrams for the plant signaling circuits regulated by G-proteins. We propose that plant G-proteins are integrated in the signaling circuits as variable resistor rather than switches, controlling the flux of information in response to the cell's metabolic state.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据