期刊
CURRENT OPINION IN PLANT BIOLOGY
卷 15, 期 5, 页码 517-522出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.pbi.2012.08.008
关键词
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资金
- National Science Foundation [MCB-1120271]
- Div Of Molecular and Cellular Bioscience
- Direct For Biological Sciences [1120271] Funding Source: National Science Foundation
Transcriptional gene silencing controls the activity of transposable elements and expression of protein-coding genes. It requires non-coding transcription, which in plants is performed by RNA Polymerases IV and V (Pol IV and Pol V). Pol IV produces precursors for siRNA biogenesis while Pol V produces scaffold transcripts required for siRNAs and associated proteins to recognize their target loci. In this review I discuss the mechanisms used by Pol IV and Pol V to mediate repressive chromatin modifications. I further discuss the mechanisms controlling non-coding transcription and their role in regulation of genome activity.
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