期刊
CURRENT OPINION IN PLANT BIOLOGY
卷 12, 期 4, 页码 414-420出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.pbi.2009.06.003
关键词
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资金
- The Gatsby Charitable Foundation
- Biotechnology and Biological Sciences Research Council [BB/F021046/1]
- ERA-NET Plant Genomies
- The Royal Society
- Two Blades Foundation
- Biotechnology and Biological Sciences Research Council [BB/F021046/1] Funding Source: researchfish
- BBSRC [BB/F021046/1] Funding Source: UKRI
In plant innate immunity, the first line of microbial recognition leading to active defence responses relies on the perception of pathogen-associated molecular patterns (PAMPs) by pattern-recognition receptors (PRRs). This recognition leads to PAMP-triggered immunity (PTI). Despite the numerous PAMPs recognised by plants, only a handful of PRRs are characterised. For most, they correspond to transmembrane proteins with a ligand-binding ectodomain. PRRs interact with additional transmembrane proteins that act as signalling adapters or amplifiers to achieve full functionality. The crucial role of PRRs in anti-microbial immunity is demonstrated by the direct targeting of PRRs and their associated proteins by pathogenic virulence effectors.
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