期刊
CURRENT OPINION IN PHARMACOLOGY
卷 12, 期 6, 页码 736-741出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.coph.2012.07.002
关键词
-
资金
- National Institutes of Health [RO1 GM088256]
The connection between the Hedgehog (HH) pathway and cholesterol has been recognized since the early days that shaped our current understanding of this unique pathway. Cholesterol and related lipids are intricately linked to HH signaling: from the role of cholesterol in HH biosynthesis to the modulation of HH signal reception and transduction by other sterols, passing by the phylogenetic relationships among many components of the HH pathway that resemble or contain lipid-binding domains. Here I review the connections between HH signaling, cholesterol and its derivatives and analyze the potential implications for HH-dependent cancers.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据