期刊
JOURNAL OF NEUROSCIENCE METHODS
卷 256, 期 -, 页码 9-21出版社
ELSEVIER
DOI: 10.1016/j.jneumeth.2015.08.015
关键词
Dense array EEG; Source localization; Minimum norm; SLORETA; FDM; Epilepsy
资金
- Electrical Geodesics, Inc.,
Background: The accuracy of EEG source localization depends on a sufficient sampling of the surface potential field, an accurate conducting volume estimation (head model), and a suitable and well-understood inverse technique. The goal of the present study is to examine the effect of sampling density and coverage on the ability to accurately localize sources, using common linear inverse weight techniques, at different depths. Several inverse methods are examined, using the popular head conductivity. New method: Simulation studies were employed to examine the effect of spatial sampling of the potential field at the head surface, in terms of sensor density and coverage of the inferior and superior head regions. In addition, the effects of sensor density and coverage are investigated in the source localization of epileptiform EEG. Results: Greater sensor density improves source localization accuracy. Moreover, across all sampling density and inverse methods, adding samples on the inferior surface improves the accuracy of source estimates at all depths. Comparison with existing methods: More accurate source localization of EEG data can be achieved with high spatial sampling of the head surface electrodes. Conclusions: The most accurate source localization is obtained when the voltage surface is densely sampled over both the superior and inferior surfaces. (C) 2015 The Authors. Published by Elsevier B.V.
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