期刊
CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY
卷 18, 期 5, 页码 357-362出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MOO.0b013e32833d11d9
关键词
cochlear otosclerosis; conductive hearing loss; mixed-type hearing loss; otic capsule; sensorineural hearing loss
资金
- NIDCD [3U24DC008559-03S109]
- International Hearing Foundation
- Starkey Foundation
Purpose of review The aim of this study is to summarize current advances in research and clinical aspects of cochlear otosclerosis. Recent findings Recent studies have revealed that otosclerosis is a process of bone remodeling that is unique to the otic capsule only. Even though no obvious bone remodeling is seen in the otic capsule under normal conditions, remodeling starts when some molecular factors trigger the capsule in certain patients who have genetic and/or environmental tendencies. Summary Cochlear otosclerosis is defined as otosclerosis located in the otic capsule involving the cochlear endosteum and causing sensorineural hearing loss or mixed-type hearing loss. It has been clearly shown that, when otosclerosis is sufficiently severe to involve the cochlear endosteum, it usually fixes the stapes as well.
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