期刊
CURRENT OPINION IN ONCOLOGY
卷 24, 期 3, 页码 266-271出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/CCO.0b013e32835167fc
关键词
chemotherapy; genetic studies; germ cell tumor; molecular genomics; nonseminomatous germ cell tumor; radiation; retroperitoneal lymph node dissection; seminoma; surveillance; survivorship
类别
资金
- Dept of Veterans Affairs
Purpose of review This overview discusses several important developments in testicular germ cell tumors in the past year. Recent findings Genomic studies continue to investigate gene expression as possible markers for disease relapse and chemotherapy resistance. Optimal treatment strategies for early-stage seminomas are evolving toward surveillance versus chemotherapy and away from radiation, and the role of retroperitoneal lymph node dissection in disseminated nonseminomatous cancers in complete remission is becoming less certain. Summary Treatment and surveillance paradigms continue to be defined and refined for both early and late-stage disease as research in these areas continues and the data from multiple large studies mature.
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