4.2 Review

Emerging roles for mammalian target of rapamycin inhibitors in the treatment of solid tumors and hematological malignancies

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Neurosciences

Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain Function

Carla Garza-Lombo et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2016)

Review Oncology

Updating progress in sarcoma therapy with mTOR inhibitors

J. -Y. Blay

ANNALS OF ONCOLOGY (2011)

Article Medicine, General & Internal

Everolimus for Advanced Pancreatic Neuroendocrine Tumors.

James C. Yao et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Oncology

Target of Rapamycin Signaling in Leukemia and Lymphoma

Collin Vu et al.

CLINICAL CANCER RESEARCH (2010)

Article Oncology

Phase II Study of Everolimus (RAD001) in Previously Treated Small Cell Lung Cancer

Ahmad Tarhini et al.

CLINICAL CANCER RESEARCH (2010)

Review Oncology

The mTOR Pathway: A New Target in Cancer Therapy

L. Ciuffreda et al.

CURRENT CANCER DRUG TARGETS (2010)

Article Cell Biology

mTOR and cancer: many loops in one pathway

Alejo Efeyan et al.

CURRENT OPINION IN CELL BIOLOGY (2010)

Review Pharmacology & Pharmacy

New inhibitors of the mammalian target of rapamycin signaling pathway for cancer

Sebastien Albert et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2010)

Article Oncology

Phase II Trial of Bevacizumab and Everolimus in Patients With Advanced Renal Cell Carcinoma

John D. Hainsworth et al.

JOURNAL OF CLINICAL ONCOLOGY (2010)

Article Oncology

Phase II Trial of Gefitinib and Everolimus in Advanced Non-small Cell Lung Cancer

Katharine A. Price et al.

JOURNAL OF THORACIC ONCOLOGY (2010)

Review Biochemistry & Molecular Biology

A comprehensive map of the mTOR signaling network

Etienne Caron et al.

MOLECULAR SYSTEMS BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

Matthew R. Janes et al.

NATURE MEDICINE (2010)

Article Medicine, General & Internal

Everolimus for Subependymal Giant-Cell Astrocytomas in Tuberous Sclerosis.

Darcy A. Krueger et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Review Biochemistry & Molecular Biology

Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy

C. A. Sparks et al.

ONCOGENE (2010)

Article Multidisciplinary Sciences

Critical roles for mTORC2-and rapamycin-insensitive mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells

Nathalie Carayol et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Clinical Neurology

Prevalence of subependymal giant cell tumors in patients with tuberous sclerosis and a review of the literature

M. E. A. P. M. Adriaensen et al.

EUROPEAN JOURNAL OF NEUROLOGY (2009)

Article Biochemistry & Molecular Biology

Common corruption of the mTOR signaling network in human tumors

S Menon et al.

ONCOGENE (2009)

Article Biochemistry & Molecular Biology

The Pharmacology of mTOR Inhibition

David A. Guertin et al.

SCIENCE SIGNALING (2009)

Article Biochemistry & Molecular Biology

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2

Morris E. Feldman et al.

PLOS BIOLOGY (2009)

Article Hematology

Exploiting the mammalian target of rapamycin pathway in hematologic malignancies

Jessica K. Altman et al.

CURRENT OPINION IN HEMATOLOGY (2008)

Editorial Material Pharmacology & Pharmacy

Mechanism of action of rapalogues: the antiangiogenic hypothesis

Sandrine Faivre et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2008)

Article Oncology

Phase II study of erlotinib in recurrent or metastatic endometrial cancer: NCICIND-148

Amit M. Oza et al.

JOURNAL OF CLINICAL ONCOLOGY (2008)

Review Oncology

Defining the role of mTOR in cancer

David A. Guertin et al.

CANCER CELL (2007)

Article Medicine, General & Internal

Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma

Gary Hudes et al.

NEW ENGLAND JOURNAL OF MEDICINE (2007)

Article Oncology

mTOR and cancer: insights into a complex relationship

David M. Sabatini

NATURE REVIEWS CANCER (2006)

Article Oncology

Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme

SM Chang et al.

INVESTIGATIONAL NEW DRUGS (2005)

Review Immunology

Mechanisms of type-I- and type-II-interferon-mediated signalling

LC Platanias

NATURE REVIEWS IMMUNOLOGY (2005)

Review Oncology

MTOR-targeted therapy of cancer with rapamycin derivatives

S Vignot et al.

ANNALS OF ONCOLOGY (2005)

Review Cell Biology

Upstream and downstream of mTOR

N Hay et al.

GENES & DEVELOPMENT (2004)

Review Oncology

The TOR pathway: A target for cancer therapy

MA Bjornsti et al.

NATURE REVIEWS CANCER (2004)