期刊
CURRENT OPINION IN NEUROLOGY
卷 26, 期 3, 页码 248-253出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/WCO.0b013e328360edb1
关键词
cutaneous allodynia; migraine; migraine pathophysiology; multisensory integration; sensitization
资金
- NIH
- American Headache Society
- National Headache Foundation
- NIH NINDS [K23NS070891]
Purpose of review Migraine attacks consist of head pain and hypersensitivities to somatosensory, visual, auditory, and olfactory stimuli. Investigating how the migraine brain simultaneously processes and responds to multiple incoming stimuli may yield insights into migraine pathophysiology and migraine symptoms. Recent findings The presence and intensity of hypersensitivity to one stimulus type are positively associated with the presence and intensity of hypersensitivities to other stimuli and to headache intensity. Furthermore, exposure to visual, auditory, and olfactory stimuli can trigger migraine attacks. These relationships suggest a role for multisensory integration in migraine. Summary Multisensory integration of somatosensory, visual, auditory, and olfactory stimuli by the migraine brain may be an important concept for understanding migraine.
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