期刊
CURRENT OPINION IN NEUROBIOLOGY
卷 21, 期 3, 页码 502-508出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2011.03.003
关键词
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资金
- EU
- Swiss National Science Foundation [310000-120791, CRSIK0-122697, CRSIK0-122691]
- Ecole Polytechnique Federale de Lausanne (EPFL)
Stress has complex effects on memory function that can vary depending on the type of information that is learned and in relation to inter-individual characteristics. Recent work has also shown that stress can switch performance between memory systems, biasing it toward habit in detriment of spatial or goal-directed strategies. In addition, novel synaptic mechanisms have been implicated in the effects of stress in plasticity and memory. Computational modeling is emerging as a useful approach to integrate and to ascertain neural and cognitive computations underlying different effects of stress in memory. Having provided novel explanations for the inverted-U-shaped relationship between stress and cognitive performance, model-based analysis studies can improve our understanding of diverse effects of stress in cognition and psychopathology.
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