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Better smelling through genetics: mammalian odor perception

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CURRENT OPINION IN NEUROBIOLOGY
卷 18, 期 4, 页码 364-369

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CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2008.09.020

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资金

  1. National Institutes of Health [DC006711, DC009600]
  2. Howard Hughes Medical Institute
  3. National Institutes of Health through the Grand Challenges in Global Health Initiative
  4. Branco Weiss Society in Science

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The increasing availability of genomic and genetic tools to study olfaction-the sense of smell-has brought important new insights into how this chemosensory modality functions in different species. Newly sequenced mammalian genomes-from platypus to dog-have made it possible to infer how smell has evolved to suit the needs of a given species and how variation within a species may affect individual olfactory perception. This review will focus on recent advances in the genetics and genomics of mammalian smell, with a primary focus on rodents and humans.

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