期刊
CURRENT OPINION IN MICROBIOLOGY
卷 16, 期 1, 页码 93-99出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.mib.2012.12.001
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资金
- NIAID NIH HHS [R01 AI099065] Funding Source: Medline
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI099065] Funding Source: NIH RePORTER
The aggregation of proteins into amyloid fibers is a common characteristic of many neurodegenerative disorders including Alzheimer's, Parkinson's, and prion diseases. Amyloid formation was originally characterized in these systems and is traditionally viewed as a consequence of protein misfolding and aggregation. An emerging field of study brings functional amyloids, like those produced by bacteria, into the scientific mainstream, and demonstrates a ubiquitous role for amyloids in living systems. This review aims to summarize what is known about the bacterial amyloids and their interactions within various host environments.
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