期刊
CURRENT OPINION IN MICROBIOLOGY
卷 16, 期 4, 页码 432-437出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.mib.2013.07.004
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资金
- Department of Science and Technology (DST)
- National Bioscience Award from the Department of Biotechnology (DBT), India
- Indo-German grant from DBT, India [BT/IN/FRG/06/PS/2009]
- National Institute of Allergies and Infectious Diseases [R01AI075459]
- DBT, EVIMalaR
- European Commission
- DST
The ability of Apicomplexan parasites to invade host cells is key to their survival and pathogenesis. Plasmodium and Toxoplasma parasites share common mechanisms for invasion of host cells. Secretion of microneme and rhoptry proteins, tight junction formation and assembly of an acto-myosin motor are key steps for successful invasion by both parasites. Here, we review our understanding of the molecular basis for these steps.
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