期刊
CURRENT OPINION IN MICROBIOLOGY
卷 13, 期 5, 页码 625-631出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.mib.2010.08.003
关键词
-
类别
资金
- Biotechnology and Biological Science Research Council [BBE0111791]
- Hospital Infection Society
- BBSRC [BB/E011179/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/E011179/1] Funding Source: researchfish
High-throughput sequencing is sweeping through clinical microbiology, transforming our discipline in its wake. It is already providing an enhanced view of pathogen biology through rapid and inexpensive whole-genome sequencing and more sophisticated applications such as RNA-seq. It also promises to deliver high-resolution genomic epidemiology as the ultimate typing method for bacteria. However, the most revolutionary effect of this 'disruptive technology' is likely to be creation of a novel sequence-based, culture-independent diagnostic microbiology that incorporates microbial community profiling, metagenomics and single-cell genomics. We should prepare for the coming 'technological singularity' in sequencing, when this technology becomes so fast and so cheap that it threatens to out-compete existing diagnostic and typing methods in microbiology.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据