期刊
CURRENT OPINION IN IMMUNOLOGY
卷 21, 期 3, 页码 346-351出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.coi.2009.05.016
关键词
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类别
资金
- NIH/NIAID [R01 AI06250]
An effective vaccine usually requires more than one time immunization in the form of prime-boost. Traditionally the same vaccines are given multiple times as homologous boosts. New findings suggested that prime-boost can be done with different types of vaccines containing the same antigens. In many cases such heterologous prime-boost can be more immunogenic than homologous prime-boost. Heterologous prime-boost represents a new way of immunization and will stimulate better understanding on the immunological basis of vaccines.
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