期刊
CURRENT OPINION IN GENETICS & DEVELOPMENT
卷 22, 期 4, 页码 354-360出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2012.04.002
关键词
-
资金
- NIH [R01 GM51186]
- ERC
- DKFZ
- University of Texas, Southwestern Medical Center
Epithelial cells of the digestive tracts of most animals are short-lived, and are constantly replenished by the progeny of long-lived, resident intestinal stem cells. Proper regulation of intestinal stem cell maintenance, proliferation and differentiation is critical for maintaining gut homeostasis. Here we review recent genetic studies of stem cell-mediated homeostatic growth in the Drosophila midgut and the mouse small intestine, highlighting similarities and differences in the mechanisms that control stem cell proliferation and differentiation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据