期刊
CURRENT OPINION IN GENETICS & DEVELOPMENT
卷 22, 期 2, 页码 139-147出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2011.11.005
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资金
- NIH [GM074213]
- Ludwig Institute for Cancer Research
- CIHR [MOP-106548]
- CCSRI [700824]
Centromeres are epigenetically defined chromatin domains marked by the presence of the histone H3 variant CENP-A. Here we review recent structural and biochemical work on CENP-A, and advances in understanding the mechanisms that propagate and read centromeric chromatin domains.
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