期刊
CURRENT OPINION IN GENETICS & DEVELOPMENT
卷 20, 期 1, 页码 41-50出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2009.12.001
关键词
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资金
- NCI [CA098830]
- US Army DOD [BC075024]
- Breast Cancer Research
In this review we discuss both gene expression and protein localization changes of polarity proteins in carcinoma. We highlight the importance of protein mislocalization and its possible role in cancer. We also discuss the emerging role of polarity proteins as regulators of proliferation, apoptosis, tissue polarity, epithelial-mesenchymal transition, in addition to their known role in cell junction biogenesis.
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