期刊
CURRENT OPINION IN CRITICAL CARE
卷 14, 期 5, 页码 587-592出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MCC.0b013e32830f1deb
关键词
antibiotics; de-escalation; infection; sepsis
Purpose of review To review the new findings on the use of antibiotics in the ICU patients. Recent findings Although there are several lines of evidence for a prompt use of antibiotics in life-threatening infections, restricting the use of antibiotics should remain the common rule. In order to reduce the emergence of multiresistant bacteria, several approaches have been tested: knowledge of local ecology, choice of the best dose of antibiotics based on their pharmacokinetic and pharmacodynamic properties, de-escalation after results of cultures, and shortening the duration of treatment. An integrative strategy including all these approaches could be associated with a reduced incidence of multiresistant bacteria. Summary Good evidence suggests that a strategy aiming at reducing the prolonged use of broad-spectrum antibiotics is the only mean to reduce the emergence of multiresistant bacteria.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据