期刊
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
卷 13, 期 3, 页码 230-235出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MCO.0b013e32833781b5
关键词
anabolic; catabolic; mTOR; NF-kappa B; skeletal muscle
资金
- NIAMS NIH HHS [R01 AR045617-08, R01 AR045617-09, R01 AR045617] Funding Source: Medline
Purpose of review The purpose of this review is to discuss recent findings as they pertain to anabolic and catabolic-signaling pathways involved in the regulation of adult skeletal muscle mass. Recent findings Research conducted over the past few years has continued to refine our understanding of the pathways that govern skeletal muscle mass, in particular the mTOR, FoxO and NF-kappa B pathways. Alternative signaling pathways have also emerged as important regulators of muscle mass such as the beta-catenin pathway. Summary A better understanding of the anabolic and catabolic processes which regulate skeletal muscle mass is critical for the development of more effective therapeutics to prevent the loss of muscle with disuse, aging and disease.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据