期刊
CURRENT OPINION IN CHEMICAL BIOLOGY
卷 19, 期 -, 页码 1-7出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2013.11.015
关键词
-
资金
- University of California, Berkeley
- Energy Biosciences Institute
Plant biomass represents a renewable carbon feedstock that could potentially be used to replace a significant level of petroleum-derived chemicals. One major challenge in its utilization is that the majority of this carbon is trapped in the recalcitrant structural polymers of the plant cell wall. Deconstruction of lignin is a key step in the processing of biomass to useful monomers but remains challenging. Microbial systems can provide molecular information on lignin depolymerization as they have evolved to break lignin down using metalloenzyme-dependent radical pathways. Both fungi and bacteria have been observed to metabolize lignin; however, their differential reactivity with this substrate indicates that they may utilize different chemical strategies for its breakdown. This review will discuss recent advances in studying bacterial lignin degradation as an approach to exploring greater diversity in the environment.
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