期刊
CURRENT OPINION IN CHEMICAL BIOLOGY
卷 12, 期 6, 页码 722-729出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2008.08.009
关键词
-
资金
- National Institutes of Health
- National Science Foundation [GM-49076, CHE-0750523]
Chemical models provide tools with which to simplify and study complicated biological systems. Forces and chemical processes that govern the structure, function, and interactions of a biomacromolecule can be explored with a simple, easy-to-study synthetic molecule. Chemical models of beta-sheet structures have helped to elucidate the factors influencing protein structures and functions. Chemical models that mimic beta-sheet quaternary structure and interactions are emerging as valuable tools with which to better understand and control protein recognition and protein aggregation.
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