期刊
CURRENT OPINION IN CELL BIOLOGY
卷 23, 期 1, 页码 85-93出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2010.10.004
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资金
- Wellcome Trust
- BBSRC
- Lowe Syndome Trust
- MRC [G117/494] Funding Source: UKRI
- Medical Research Council [G117/494] Funding Source: researchfish
The Golgi apparatus is a universal feature of eukaryotes, carrying out the key functions of processing, sorting and trafficking of newly synthesized membrane and secretory proteins. The Golgi apparatus has a clearly defined structure, comprising stacks of flattened cisternal membranes that in Vertebrates are connected to form a ribbon. How this structure is maintained and how it relates to the functions of the Golgi apparatus has long been an area of interest. In this review I describe recent progress in the identification and characterization of the molecular machinery that together help generate the characteristic organization of this organelle.
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