期刊
CURRENT OPINION IN CELL BIOLOGY
卷 22, 期 2, 页码 169-176出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2009.10.007
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资金
- NIH
- HHMI
- Human Frontiers Science Program
The mammalian target of rapamycin (mTOR) is a master regulator of cell growth and division that responds to a variety of stimuli, including nutrient, energy, and growth factors. In the last years, a significant number of pieces have been added to the puzzle of how mTOR coordinates and executes its functions. Extensive research on mTOR has also uncovered a complex network of regulatory loops that impact the therapeutic approaches aimed at targeting mTOR.
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