期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 28, 期 -, 页码 51-58出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2013.11.005
关键词
-
资金
- NSF [1264701, 1011509]
- Direct For Education and Human Resources
- Division Of Graduate Education [1011509] Funding Source: National Science Foundation
- Directorate For Engineering
- Div Of Chem, Bioeng, Env, & Transp Sys [1264701] Funding Source: National Science Foundation
Vaccine adjuvants are an essential component of vaccine design, helping to generate immunity to pathogen antigens in the absence of infection. Recent advances in nanoscale engineering have created a new class of particulate bionanotechnology that uses biomimicry to better integrate adjuvant and antigen. These pathogen-like particles, or PLPs, can come from a variety of sources, ranging from fully synthetic platforms to biologically derived, self-assembling systems. By employing molecularly engineered targeting and stimulation of key immune cells, recent studies utilizing PLPs as vaccine delivery platforms have shown great promise against high-impact, unsolved vaccine targets ranging from bacterial and viral pathogens to cancer and addiction.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据