期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 27, 期 -, 页码 115-122出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2014.01.003
关键词
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资金
- U. S. Army Research Laboratory
- U. S. Army Research Office [W911NF-12-1-0555]
- Cornell University Agricultural Experiment Station federal formula funds, from the National Institutes for Food and Agriculture (NIFA), U.S. Department of Agriculture [NYC-123452]
- European Research Council Starter Grant Electrotalk
- Multidisciplinary Research Partnership Ghent Bio-Economy
- Chemical Sciences division of the Netherlands Science Foundation [CW-TOP 700.55.343]
- European Research Council (ERC) [323009]
Different microbial pathways can elongate the carbon chains of molecules in open cultures of microbial populations (i.e. reactor nnicrobionnes) under anaerobic conditions. Here, we discuss three such pathways: 1. homoacetogenesis to combine two carbon dioxide molecules into acetate; 2. succinate formation to elongate glycerol with one carbon from carbon dioxide; and 3. reverse beta oxidation to elongate short-chain carboxylates with two carbons into medium-chain carboxylates, leading to more energy-dense and insoluble products (e.g. easier to separate from solution). The ability to use reactor microbiomes to treat complex substrates can simultaneously address two pressing issues: 1. providing proper waste management; and 2. producing renewable chemicals and fuels.
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