期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 29, 期 -, 页码 124-131出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2014.04.004
关键词
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资金
- National Basic Research Program of China [2011CBA00800]
- National High-tech Research and Development Program of China [2011AA02A208]
- National Natural Science Foundation of China [31100062, 31121001, 31370133]
- SA-SIBS Scholarship Program
Solventogenic clostridia can produce acetone, butanol and ethanol (ABE) by using different carbohydrates. For economical reasons, the utilization of cheap and renewable biomass in clostridia-based ABE fermentation has recently attracted increasing interests. With the study of molecular microbiology and development of genetic tools, the understanding of carbohydrate metabolism in clostridia has increased in recent years. Here, we review the pioneering work in this field, with a focus on dissecting the pathways and describing the regulation of the metabolism of economical substrate-derived carbohydrates by clostridia. Recent progress in the metabolic engineering of carbohydrate utilization pathways is also described.
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