期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 21, 期 5, 页码 657-662出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.copbio.2010.05.008
关键词
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资金
- BioEnergy Science Center (BESC)
- Office of Biological and Environmental Research in the DOE Office of Science
- UT-Battelle LLC for the U.S. D.O.E. [DE-AC05-00OR22725]
In order for plant biomass to become a viable feedstock for meeting the future demand for liquid fuels, efficient and cost-effective processes must exist to breakdown cellulosic materials into their primary components. A one-pot conversion strategy or, consolidated bioprocessing, of biomass into ethanol would provide the most cost-effective route to renewable fuels and the realization of this technology is being actively pursued by both multi-disciplinary research centers and industrialists working at the very cutting edge of the field. Although a diverse range of bacteria and fungi possess the enzymatic machinery capable of hydrolyzing plant-derived polymers, none discovered so far meet the requirements for an industrial strength biocatalyst for the direct conversion of biomass to combustible fuels. Synthetic biology combined with a better fundamental understanding of enzymatic cellulose hydrolysis at the molecular level is enabling the rational engineering of microorganisms for utilizing cellulosic materials with simultaneous conversion to fuel.
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