期刊
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
卷 8, 期 5, 页码 371-376出版社
SPRINGER
DOI: 10.1007/s11910-008-0058-2
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资金
- NINDS NIH HHS [T32 NS007338-19, T32 NS007338] Funding Source: Medline
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [T32NS007338] Funding Source: NIH RePORTER
Normal pressure hydrocephalus (NPH) is a syndrome of gait dysfunction and enlarged cerebral ventricles in the absence of another cause. It is frequently accompanied by frontal and subcortical cognitive deficits and bladder detrusor overactivity. NPH is rare relative to other potential causes of these symptoms in the elderly, but timely diagnosis can lead to reversal of symptoms through ventricular shunting. There are many tests used to predict possible response to surgery, such as MRI of the brain, formalized neuropsychological and gait testing, large-volume lumbar puncture, and prolonged lumbar drainage, but no one test has been validated to rule out potential response to surgery.
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