期刊
CURRENT EYE RESEARCH
卷 33, 期 9, 页码 727-735出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/02713680802326606
关键词
atelocollagen; collagen fibril; corneal regeneration; dog; keratocyte
Purpose: To evaluate the effectiveness of atelocollagen for canine corneal wound healing. Materials and Methods: Atelocollagen was used to fill a transplant bed in the central cornea, which was then covered with a contact lens. The wound healing process was analyzed clinically, morphologically, and biochemically. Results: At the early healing stage, both the pupillary zone and details of the iris were observed. The stromal collagen fibrils normalized in a time-dependent manner. Type III collagen in the wound area was detected faintly throughout the experimental period. Conclusions: This novel method is advantageous for accelerating wound healing without causing inflammation.
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