期刊
CURRENT BIOLOGY
卷 21, 期 16, 页码 1397-1402出版社
CELL PRESS
DOI: 10.1016/j.cub.2011.07.019
关键词
-
资金
- Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan [16002001, 20002001]
- Global Center of Excellence of MEXT [A08, D10]
- Japan Society for the Promotion of Science [21-3916]
- Grants-in-Aid for Scientific Research [23220006] Funding Source: KAKEN
A comparison of developmental patterns of white matter (WM) within the prefrontal region between humans and non-human primates is key to understanding human brain evolution. WM mediates complex cognitive processes and has reciprocal connections with posterior processing regions [1, 2]. Although the developmental pattern of prefrontal WM in macaques differs markedly from that in humans [3], this has not been explored in our closest evolutionary relative, the chimpanzee. The present longitudinal study of magnetic resonance imaging scans demonstrated that the prefrontal WM volume in chimpanzees was immature and had not reached the adult value during prepuberty, as observed in humans but not in macaques. However, the rate of prefrontal WM volume increase during infancy was slower in chimpanzees than in humans. These results suggest that a less mature and more protracted elaboration of neuronal connections in the prefrontal portion of the developing brain existed in the last common ancestor of chimpanzees and humans, and that this served to enhance the impact of postnatal experiences on neuronal connectivity. Furthermore, the rapid development of the human prefrontal WM during infancy may help the development of complex social interactions, as well as the acquisition of experience-dependent knowledge and skills to shape neuronal connectivity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据