4.4 Review

Gender Differences in Ischemic Cardiomyopathy

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CURRENT ATHEROSCLEROSIS REPORTS
卷 20, 期 10, 页码 -

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CURRENT MEDICINE GROUP
DOI: 10.1007/s11883-018-0750-x

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Women; Gender; Coronary artery disease; Heart failure; Ischemic cardiomyopathy; Gender disparities

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Purpose of ReviewCardiovascular disease remains the leading cause of death among women globally, majority of which are due to ischemic heart disease. Despite the recent advances in the overall management of CVD, there are unique challenges in the diagnosis and management of women as well as poorer outcomes.Recent FindingsWomen with ischemic cardiomyopathy experience significant morbidity and mortality. Differences in underlying pathology, delays in presentation, diagnosis, and treatment as well as the under-representation of women in clinical trials contribute to these poor outcomes.SummaryIn this review, we discuss the nuances of gender-specific differences in the burden, clinical presentation, and outcomes of ischemic cardiomyopathy in women, in addition to discussion of areas needing further research.

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