期刊
CURRENT ANALYTICAL CHEMISTRY
卷 5, 期 2, 页码 116-130出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157341109787846117
关键词
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In this work, the bottom-up protein identification process is described, from sample digestion to the final database search result. Both MALDI and LC-MS approaches to the identification issue are illustrated. The state-of-the-art of these technique is outlined along with several recent applications, such as MSn data acquisition and chemical derivatization of peptides.
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