期刊
CRYSTAL GROWTH & DESIGN
卷 13, 期 4, 页码 1551-1557出版社
AMER CHEMICAL SOC
DOI: 10.1021/cg301798s
关键词
-
资金
- Bose Fellowship [SR/S2/JCB-06/2009]
- CSIR Pharmaceutical Cocrystals [01(2410)/10/EMR-II]
4-Aminosalicylic acid (p-aminosalicylic acid, PAS), an antituberculosis drug, is a model active pharmaceutical ingredient to study salt and cocrystal formation in a multiple hydrogen-bonding functionality molecule with carboxylic acid, amine, and phenol groups. A cytosine salt CYT+-PAS(-), salt cocrystal hydrate CWT+-PAS(-)-CYT-H2O, and nicotinamide cocrystal hydrate PAS-NAM-H2O, are described in this article. Furthermore, X-ray crystal structures of PAS sodium dihydrate, sulfate, and mesylate salts and dehydration/rehydration behavior of the sodium salt by powder X-ray diffraction are discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据