期刊
JOURNAL OF NATURAL PRODUCTS
卷 78, 期 8, 页码 2136-2140出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.jnatprod.5b00239
关键词
-
资金
- Universite Paris Descartes, Sorbonne Paris Cite
Two regioisomeric polycydic xanthones, 3,16-oxyguttiferone A (2) and 1,16-oxyguttiferone A (3), which are polyprenylated acylphloroglucinol-derived analogues, were isolated from the seeds of Symphonia globulifera, together with their presumed o-dihydroxybenzoyl precursor, guttiferone A (1). Anodic oxidation of 1 into the corresponding o-quinone species proved to be an efficient biomimetic method to generate xanthones 2 and 3 in high overall yield and to confirm their structures. Both compounds displayed cytotoxicity against the HCT 116 colon carcinoma cell line with IC50 values of 8 and 3 mu M, respectively.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据