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Confirmation of the stereostructure of (+)-cytostatin by fluorous mixture synthesis of four candidate stereoisomers
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Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic β-cells
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Arabidopsis PPP family of serine/threonine phosphatases
Ilona Farkas et al.
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Evolution of the metazoan protein phosphatase 2C superfamily
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Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: Impact on PP2A inhibition
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Structure of the protein phosphatase 2A holoenzyme
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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
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Protein tyrosine phosphatases: from genes, to function, to disease
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Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins
Yongna Xing et al.
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The α4 regulatory subunit exerts opposing allosteric effects on protein phosphatases PP6 and PP2A
Todd D. Prickett et al.
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Cytotoxicity of cantharidin analogues targeting protein phosphatase 2A
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Protein phosphatase 6 subunit with conserved sit4-associated protein domain targets IκBε
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Crystal structures of protein phosphatase-1 bound to motuporin and dihydromicrocystin-LA: Elucidation of the mechanism of enzyme inhibition by cyanobacterial toxins
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Targeting the PTPome in human disease
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Inhibition of several protein phosphatases by a non-covalently interacting microcystin and a novel cyanobacterial peptide, nostocyclin
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Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein
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Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
F Liu et al.
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A B56 regulatory subunit of protein phosphatase 2A localizes to nuclear speckles in cardiomyocytes
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A structural perspective of CTD function
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Protein phosphatase 4 -: from obscurity to vital functions
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FEBS LETTERS (2005)
Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
JP MacKeigan et al.
NATURE CELL BIOLOGY (2005)
Phoslactomycin targets cysteine-269 of the protein phosphatase 2A catalytic subunit in cells
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Molecular basis for TPR domain-mediated regulation of protein phosphatase
J Yang et al.
EMBO JOURNAL (2005)
Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole
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A gene atlas of the mouse and human protein-encoding transcriptomes
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DNA-PKcs function regulated specifically by protein phosphatase 5
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Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation
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Phylogenetic evidence for the early evolution of microcystin synthesis
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Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity
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Structure and mechanism of RNA polymerase IICTD phosphatases
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Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade
GF Zhou et al.
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Structural basis of protein phosphatase 1 regulation
M Terrak et al.
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Total synthesis and biological evaluation of the protein phosphatase 2A inhibitor cytostatin and analogues
L Bialy et al.
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Crystal structure and mutagenesis of a protein phosphatase-1:calcineurin hybrid elucidate the role of the β12-β13 loop in inhibitor binding
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G Urban et al.
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J Yang et al.
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Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin
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Evolution of protein kinase signaling from yeast to man
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Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes
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Immunosuppressive effects of tautomycetin in vivo and in vitro via T cell-specific apoptosis induction
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Two conserved domains in regulatory B subunits mediate binding to the A subunit of protein phosphatase 2A
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Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1
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Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress
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Impact of a toxic and a non-toxic strain of Microcystis aeruginosa on the crayfish Procambarus clarkii
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