期刊
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
卷 86, 期 3, 页码 212-221出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.critrevonc.2012.11.004
关键词
Angiogenesis; Anti-angiogenesis; Neuroblastoma; Tumour growth
资金
- European Union Seventh Framework programme (FPT7) [278570]
The nature of the angiogenic balance in neuroblastoma is complex, and a spectrum of angiogenesis stimulators and inhibitors have been detected in neuroblastoma tumours. The complex relationships between angiogenic cascade and anti-angiogenic agents in the tumour vascular phase have indicated that anti-angiogenesis can be considered as a strategy for the adjuvant therapy of neuroblastoma. The major goal is to establish if inhibition of angiogenesis is a realistic therapeutic strategy for inhibiting tumour cell dissemination and the formation of metastasis in neuroblastoma. (c) 2012 Elsevier Ireland Ltd. All rights reserved.
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