期刊
CRITICAL REVIEWS IN MICROBIOLOGY
卷 41, 期 2, 页码 140-149出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/1040841X.2013.813898
关键词
Biosorption; cell surface display; heavy metal removal
类别
资金
- Shenzhen municipal government [CXB201111240110A, JCYJ20130329174424934]
Heavy metal contamination has become a worldwide environmental concern due to its toxicity, non-degradability and food-chain bioaccumulation. Conventional physical and chemical treatment methods for heavy metal removal have disadvantages such as cost-intensiveness, incomplete removal, secondary pollution and the lack of metal specificity. Microbial biomass-based biosorption is one of the approaches gaining increasing attention because it is effective, cheap, and environmental friendly and can work well at low concentrations. To enhance the adsorption properties of microbial cells to heavy metal ions, the cell surface display of various metal-binding proteins/peptides have been performed using a cell surface engineering approach. The surface engineering of Gram-negative bacteria, Gram-positive bacteria and yeast towards the adsorption of heavy metals are reviewed in this article. The problems and future perspectives of this technology are discussed.
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