期刊
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
卷 53, 期 10, 页码 1077-1096出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/10408398.2012.742861
关键词
Selenium; nutrition; dietary reference values; selenoprotein P; glutathione peroxidase; plasma selenium; serum selenium; requirements
资金
- Commission of the European Communities, specific RTD Programme Quality of Life and Management of Living Resources, within the 6th Framework Programme [FP6-036196-2]
- Biotechnology and Biological Sciences Research Council [BBS/E/F/00042669] Funding Source: researchfish
- BBSRC [BBS/E/F/00042669] Funding Source: UKRI
Current reference values for selenium, an essential micronutrient, are based on the intake of selenium that is required to achieve maximal glutathione peroxidase activity in plasma or erythrocytes. In order to assess the evidence of relevance to setting dietary reference values for selenium, the EURRECA Network of Excellence focused on systematic searches, review, and evaluation of (i) selenium status biomarkers and evidence for relationships between intake and status biomarkers, (ii) selenium and health (including the effect of intake and/or status biomarkers on cancer risk, immune function, HIV, cognition, and fertility), (iii) bioavailability of selenium from the diet, and (iv) impact of genotype/single nucleotide polymorphisms on status or health outcomes associated with selenium. The main research outputs for selenium and future research priorities are discussed further in this review.
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