期刊
CRITICAL REVIEWS IN BIOTECHNOLOGY
卷 34, 期 3, 页码 258-268出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/07388551.2013.791660
关键词
Activity; applications; biotechnological production; microbe; phenylalanine ammonia lyase; purification; stability
资金
- National Natural Science Foundation of China (NSFC) [21072041]
- Open Funding Project of the National Key Laboratory of Biochemical Engineering [KF2010-12]
- Foundation of Tianjin Key Laboratory of Industrial Microbiology (Tianjin University of Science and Technology), P. R. China [2012IM004]
- Foundation of Hebei University of Science and technology for Distinguished Young Scientists
Phenylalanine ammonia lyase (PAL) catalyzes the nonoxidative deamination of L-phenylalanine to form trans-cinnamic acid and a free ammonium ion. It plays a major role in the catabolism of L-phenylalanine. The presence of PAL has been reported in diverse plants, some fungi, Streptomyces and few Cyanobacteria. In the past two decades, PAL has gained considerable significance in several clinical, industrial and biotechnological applications. Since its discovery, much knowledge has been gathered with reference to the enzyme's importance in phenyl propanoid pathway of plants. In contrast, there is little knowledge about microbial PAL. Furthermore, the commercial source of the enzyme has been mainly obtained from the fungi. This study focuses on the recent advances on the physiological role of microbial PAL and the improvements of PAL biotechnological production both from our laboratory and many others as well as the latest advances on the new applications of microbial PAL.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据