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Inhibitory effect of salmosin, a Korean snake venom-derived disintegrin, on the integrin αv-mediated proliferation of SK-Mel-2 human melanoma cells
KH Chung et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2003)
An assessment of ADAMs in bone cells:: absence of TACE activity prevents osteoclast recruitment and the formation of the marrow cavity in developing long bones
P Boissy et al.
FEBS LETTERS (2003)
ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating β1 integrin function
N Kawaguchi et al.
JOURNAL OF CELL SCIENCE (2003)
Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-α-converting enzyme (ADAM 17)
KJ Garton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
TACE is required for fetal murine cardiac development and modeling
W Shi et al.
DEVELOPMENTAL BIOLOGY (2003)
Targeted overexpression of transmembrane tumor necrosis factor provokes a concentric cardiac hypertrophic phenotype
ZI Dibbs et al.
CIRCULATION (2003)
TACE/ADAM-17 enzymatic activity is increased in response to cellular stimulation
JR Doedens et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
The disintegrin-like metalloproteinase ADAM 10 is involved in coinstitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion
C Hundhausen et al.
BLOOD (2003)
BaG, a new dimeric metalloproteinase/disintegrin from the Bothrops alternatus snake venom that interacts with α5β1 integrin
MR Cominetti et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Impaired trafficking and activation of tumor necrosis factor-α-converting enzyme in cell mutants defective in protein ectodomain shedding
A Borroto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Tobacco smoke-induced lung cell proliferation mediated by tumor necrosis factor α-converting enzyme and amphiregulin
H Lemjabbar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and γ-secretase
E Six et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Back signaling by the Nrg-1 intracellular domain
JX Bao et al.
JOURNAL OF CELL BIOLOGY (2003)
Snake venom disintegrins: novel dimeric disintegrins and structural diversification by disulphide bond engineering
JJ Calvete et al.
BIOCHEMICAL JOURNAL (2003)
Histamine antagonizes tumor necrosis factor (TNF) signaling by stimulating TNF receptor shedding from the cell surface and Golgi storage pool
J Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling
LF Jackson et al.
EMBO JOURNAL (2003)
Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-α converting enzyme and of an alternatively translated polypeptide
HZ Fan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of SAP97 as an intracellular binding partner of TACE
F Peiretti et al.
JOURNAL OF CELL SCIENCE (2003)
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
A Gschwind et al.
EMBO JOURNAL (2003)
Intracellular maturation and transport of tumor necrosis factor alpha converting enzyme
F Peiretti et al.
EXPERIMENTAL CELL RESEARCH (2003)
In situ localization of TNFα/β, TACE and TNF receptors TNF-R1 and TNF-R2 in control and LPS-treated lung tissue
M Ermert et al.
CYTOKINE (2003)
The deaf and the dumb: the biology of ErbB-2 and ErbB-3
A Citri et al.
EXPERIMENTAL CELL RESEARCH (2003)
TACE is required for the activation of the EGFR by TGF-α in tumors
M Borrell-Pagès et al.
EMBO JOURNAL (2003)
Negative impact of tissue inhibitor of metalloproteinase-3 null mutation on lung structure and function in response to sepsis
EL Martin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2003)
Functional effect of contortrostatin, a snake venom disintegrin, on human glioma cell invasion in vitro
S Schmitmeier et al.
CELL COMMUNICATION AND ADHESION (2003)
Metalloprotease-mediated GH receptor proteolysis and GHBP shedding - Determination of extracellular domain stem region cleavage site
XD Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The cysteine-rich domain regulates ADAM protease function in vivo
KM Smith et al.
JOURNAL OF CELL BIOLOGY (2002)
TACE mRNA expression in peripheral mononudear cells precedes new lesions on MRI in multiple sclerosis
T Seifert et al.
MULTIPLE SCLEROSIS (2002)
Evidence for regulation of the tumor necrosis factor α-convertase (TACE) by protein-tyrosine phosphatase PTPH1
YF Zheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Discovery of γ-lactam hydroxamic acids as selective inhibitors of tumor necrosis factor α converting enzyme:: Design, synthesis, and structure-activity relationships
JJW Duan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Upregulation of TACE/ADAM17 after ischemic preconditioning is involved in brain tolerance
A Cárdenas et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2002)
The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3
MH Lee et al.
FEBS LETTERS (2002)
Extracellular signal-regulated kinase phosphorylates tumor necrosis factor α-converting enzyme at threonine 735:: A potential role in regulated shedding
E Díaz-Rodríguez et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
TACE/ADAM17-TNF-α pathway in rat cortical cultures after exposure to oxygen-glucose deprivation or glutamate
O Hurtado et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2002)
A physiologic signaling role for the γ-secretase-derived intracellular fragment of APP
MA Leissring et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Pharmacological profile of PKF242-484 and PKF241-466, novel dual inhibitors of TNF-α converting enzyme and matrix metalloproteinases, in models of airway inflammation
A Trifilieff et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
Differential effects between marimastat, a TNF-α converting enzyme inhibitor, and anti-TNF-α antibody on murine models for sepsis and arthritis
F Tsuji et al.
CYTOKINE (2002)
ADAMs (A disintegrin and metalloproteinase) messenger RNA expression in Helicobacter pylori-infected, normal, and neoplastic gastric mucosa
T Yoshimura et al.
JOURNAL OF INFECTIOUS DISEASES (2002)
Effect of TNF-α-converting enzyme inhibitor on insulin resistance in fructose-fed rats
N Togashi et al.
HYPERTENSION (2002)
The increase in TNF-α levels is implicated in NF-κB activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress
JLM Madrigal et al.
NEUROPSYCHOPHARMACOLOGY (2002)
Angiotensin II signaling and HB-EGF shedding via metalloproteinase in glomerular mesangial cells
Y Uchiyama-Tanaka et al.
KIDNEY INTERNATIONAL (2001)
Design of selective and soluble inhibitors of tumor necrosis factor-α converting enzyme (TACE)
MH Rabinowitz et al.
JOURNAL OF MEDICINAL CHEMISTRY (2001)
Neuronal localization of the TNFα converting enzyme (TACE) in brain tissue and its correlation to amyloid plaques
DM Skovronsky et al.
JOURNAL OF NEUROBIOLOGY (2001)
Implication of APP secretases in notch signaling
D Hartmann et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2001)
A novel inhibitor of tumor necrosis factor-α converting enzyme ameliorates polycystic kidney disease
KM Dell et al.
KIDNEY INTERNATIONAL (2001)
Inhibition of matrix metalloproteinases and tumour necrosis factor α converting enzyme as adjuvant therapy in pneumococcal meningitis
SL Leib et al.
BRAIN (2001)
Design, synthesis, and structure-activity relationships of macrocyclic hydroxamic acids that inhibit tumor necrosis factor α release in vitro and in vivo
CB Xue et al.
JOURNAL OF MEDICINAL CHEMISTRY (2001)
Transendothelial migration of lymphocytes across high endothelial venules into lymph nodes is affected by metalloproteinases
C Faveeuw et al.
BLOOD (2001)
Up-regulation of TNF-α convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices
O Hurtado et al.
NEUROPHARMACOLOGY (2001)
Astrocyte and endothelial cell expression of ADAM 17 (TACE) in adult human CNS
DR Goddard et al.
GLIA (2001)
Pulmonary hypoplasia in mice lacking tumor necrosis factor-α converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis
JS Zhao et al.
DEVELOPMENTAL BIOLOGY (2001)
ADAM17 but not ADAM10 mediates tumor necrosis factor-α and L-selectin shedding from leukocyte membranes
TP Condon et al.
ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT (2001)
TNF-α-converting enzyme cleaves the macrophage colony-stimulating factor receptor in macrophages undergoing activation
E Rovida et al.
JOURNAL OF IMMUNOLOGY (2001)
Expression of tumor necrosis factor-alpha-converting enzyme and tumor necrosis factor-alpha in human myocarditis
M Satoh et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2000)
Metalloprotease-disintegrin (ADAM) genes are widely and differentially expressed in the adult CNS
I Kärkkäinen et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2000)
Stimulation-induced down-regulation of tumor necrosis factor-α converting enzyme
JR Doedens et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Functional analysis of the domain structure of tumor necrosis factor-α converting enzyme
P Reddy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation:: Evidence in Crohn disease and experimental colitis in vivo
R Atreya et al.
NATURE MEDICINE (2000)
Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis
BB Chen et al.
NATURE GENETICS (2000)
A novel proteolytic cleavage involved in Notch signaling:: The role of the disintegrin-metalloprotease TACE
C Brou et al.
MOLECULAR CELL (2000)
A role for Smad6 in development and homeostasis of the cardiovascular system
KM Galvin et al.
NATURE GENETICS (2000)
Contortrostatin, a homodimeric disintegrin, binds to integrin αvβ5
Q Zhou et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Decreased insulin production and increased insulin sensitivity in the Klotho mutant mouse, a novel animal model for human aging
T Utsugi et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2000)
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