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BIOLOGICAL TRACE ELEMENT RESEARCH (2008)
Melatonin, hormone of darkness and more - occurrence, control mechanisms, actions and bioactive metabolites
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Potential role of tryptophan derivatives in stress responses characterized by the generation of reactive oxygen and nitrogen species
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Role of melatonin in regulating matrix metalloproteinase-9 via tissue inhibitors of metalloproteinase-1 during protection against endometriosis
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Effect of melatonin on apoptosis, proliferation and differentiation of urothelial cells after cyclophosphamide treatment
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Utility of melatonin to treat surgical stress after major vascular surgery -: a safety study
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Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate
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The oxidation products of melatonin derivatives exhibit acetylcholinesterase and butyrylcholinesterase inhibitory activity
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Melatonin mitigates oxidative damage and apoptosis in mouse cerebellum induced by high-LET 56Fe particle irradiation
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Melatonin preserves superoxide dismutase activity in hypoglossal motoneurons of adult rats following peripheral nerve injury
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Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats
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Melatonin uptake in prostate cancer cells:: intracellular transport versus simple passive diffusion
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Hyperglycemia-Related Pathophysiologic Mechanisms and Potential Beneficial Actions of Melatonin
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MINI-REVIEWS IN MEDICINAL CHEMISTRY (2008)
Melatonin and the Immune System in Aging
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Stevens-Johnson syndrome and toxic epidermal necrolysis induced by amifostine during head and neck radiotherapy
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Melatonin in the skin: synthesis, metabolism and functions
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Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis
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JOURNAL OF PINEAL RESEARCH (2007)
Melatonin inhibits free radical-mediated mitochondrial-dependent hepatocyte apoptosis and liver damage induced during malarial infection
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Foundation review: Trends in the development of radioprotective agents
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JOURNAL OF CLINICAL ONCOLOGY (2007)
Alpha-tocopherol, beta-carotene and melatonin administration protects cyclophosphamide-induced oxidative damage to bladder tissue in rats
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A unicenter, randomized, double-blind, parallel-group, placebo-controlled study of Melatonin as an Adjunct in patients with acute myocaRdial Infarction undergoing primary Angioplasty - The Melatonin Adjunct in the acute myocaRdial Infarction treated with Angioplasty (MARIA) trial: Study design and rationale
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CONTEMPORARY CLINICAL TRIALS (2007)
Novel rhythms of N1-acetyl-N2-formyl-5-methoxykynuramine and its precursor melatonin in water hyacinth:: importance for phytoremediation
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FASEB JOURNAL (2007)
AFMK, a melatonin metabolite, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice
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JOURNAL OF PINEAL RESEARCH (2007)
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Expression and cellular localization of melatonin-synthesizing enzymes in the rat lens
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Evidence supporting the use of melatonin in short gestation infants
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Amifostine: The first selective-target and broad-spectrum radioprotector
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Do carotenoid-based sexual traits signal the availability of non-pigmentary antioxidants?
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Reduced oxidative damage in ALS by high-dose enteral melatonin treatment
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Interactions of melatonin and its metabolites with the ABTS cation radical: extension of the radical scavenger cascade and formation of a novel class of oxidation products, C2-substituted 3-indolinones
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Melatonin arrests peroxynitrite-induced tau hyperphosphorylation and the overactivation of protein kinases in rat brain
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Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin
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FEBS JOURNAL (2006)
Constitutive and UV-induced metabolism of melatonin in keratinocytes and cell-free systems
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FASEB JOURNAL (2006)
Melatonin directly scavenges free radicals generated in red blood cells and a cell-free system: Chemiluminescence measurements and theoretical calculations
I. B. Zavodnik et al.
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Apoptosis in liver during malaria: role of oxidative stress and implication of mitochondrial pathway
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FASEB JOURNAL (2006)
Effects of melatonin and Vitamin E on oxidative-antioxidative status in rats exposed to irradiation
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Urinary metabolites and antioxidant products of exogenous melatonin in the mouse
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Melatonin attenuates diabetes-induced oxidative stress in rabbits
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Protective effects of melatonin in experimental free radical-related ocular diseases
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Reactions of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK) with the ABTS cation radical:: identification of new oxidation products
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Mitochondrial damage induced by fetal hyperphenylalaninemia in the rat brain and liver:: Its prevention by melatonin, Vitamin E, and Vitamin C
F Martínez-Cruz et al.
NEUROSCIENCE LETTERS (2006)
Melatonin as a cytoskeletal modulator: implications for cell physiology and disease
G Benitez-King
JOURNAL OF PINEAL RESEARCH (2006)
Protective effects of melatonin on γ-ray induced intestinal damage
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INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2005)
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ENDOCRINE (2005)
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ENDOCRINE (2005)
Melatonin ameliorates bladder damage induced by cyclophosphamide in rats
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Antioxidant capacity of the neurohormone melatonin
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Melatonin mitigates mitochondrial malfunction
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Oxidative and inflammatory parameters in respiratory distress syndrome of preterm newborns:: Beneficial effects of melatonin
E Gitto et al.
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Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes
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JOURNAL OF PINEAL RESEARCH (2004)
Melatonin and mitochondrial function
J Leon et al.
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Melatonin as a radioprotective agent: A review
Vijayalaxmi et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2004)
Regulation of antioxidant enzymes: a significant role for melatonin
C Rodriguez et al.
JOURNAL OF PINEAL RESEARCH (2004)
Oxidation of melatonin and its catabolites, N1-acetyl-N 2-formyl-5-methoxykynuramine and N1-acetyl-5-methoxykynuramine, by activated leukocytes
SO Silva et al.
JOURNAL OF PINEAL RESEARCH (2004)
Digging deep - structure-function relationships in the melatonin receptor family
P Barrett et al.
JOURNAL OF PINEAL RESEARCH (2003)
Clock genes in calendar cells as the basis of annual timekeeping in mammals - a unifying hypothesis
GA Lincoln et al.
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Orally administered melatonin reduces oxidative stress and proinflammatory cytokines induced by amyloid-β peptide in rat brain:: a comparative, in vivo study versus vitamin C and E
S Rosales-Corral et al.
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Protective effects of melatonin, vitamin E and N-acetylcysteine against acetaminophen toxicity in mice:: a comparative study
G Sener et al.
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Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical
DX Tan et al.
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Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and α-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents:: a study of their individual and synergistic actions
S López-Burillo et al.
JOURNAL OF PINEAL RESEARCH (2003)
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JOURNAL OF PINEAL RESEARCH (2003)
Melatonin does not directly scavenge hydrogen peroxide: Demise of another myth
G Fowler et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Oxidation of melatonin by carbonate radicals and chemiluminescence emitted during pyrrole ring cleavage
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M Allegra et al.
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N-1-acetyl-N-2-formyl-5-methoxykynuramine is a product of melatonin oxidation in rats
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Melatonin protects against myocardial doxorubicin toxicity in rats: role of physiological concentrations
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GA Bubenik
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Protective effects of melatonin on myocardial ischemia/reperfusion injury in vivo
YM Lee et al.
JOURNAL OF PINEAL RESEARCH (2002)
Oxidative stress induced by phenylketonuria in the rat: Prevention by melatonin, vitamin E, and vitamin C
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JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Daily rhythm of glutathione peroxidase activity, lipid peroxidation and glutathione levels in tissues of pinealectomized rats
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NEUROSCIENCE LETTERS (2002)
Comparative analysis of the protective effects of melatonin and vitamin E on streptozocin-induced diabetes mellitus
G Baydas et al.
JOURNAL OF PINEAL RESEARCH (2002)
Effects of physiological and pharmacological concentrations of melatonin on ischemia-reperfusion arrhythmias in rats: can the incidence of sudden cardiac death be reduced?
E Sahna et al.
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The effect of melatonin on the secretion of progesterone in sheep and on the development of ovine embryos in vitro
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Melatonin attenuates MPTP-induced dopaminergic neuronal injury associated with scavenging hydroxyl radical
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Causes of oxidative stress in the pre- and perinatal period
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Effects of melatonin treatment in septic newborns
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PEDIATRIC RESEARCH (2001)
Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: reduction by melatonin
F Fulia et al.
JOURNAL OF PINEAL RESEARCH (2001)
Oxidation of melatonin and tryptophan by an HRP cycle involving compound III
VF Ximenes et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Melatonin protects against ischemia/reperfusion-induced oxidative damage to mitochondria in fetal rat brain
A Wakatsuki et al.
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Melatonin versus treatment against extra-hepatic bile vitamin E as protective oxidative stress after duct ligation in rats
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Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury
S Cuzzocrea et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2001)
Prooxidant activity of melatonin promotes fas-induced cell death in human leukemic Jurkat cells
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FEBS LETTERS (2001)
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E Gitto et al.
INTENSIVE CARE MEDICINE (2001)
Presence of melatonin in the human hepatobiliary-gastrointestinal tract
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Melatonin acts as antioxidant and prooxidant in an organotypic slice culture model of Alzheimer's disease
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Gene expression of the key enzymes of melatonin synthesis in extrapineal tissues of the rat
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Endogenous rhythms of melatonin, total antioxidant status and superoxide dismutase activity in several tissues of chick and their inhibition by light
MT Albarrán et al.
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In vivo changes in antioxidant systems and protective role of melatonin and a combination of vitamin C and vitamin E on oxidative damage in erythrocytes induced by chlorpyrifos-ethyl in rats
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Melatonin prevents δ-aminolevulinic acid-induced oxidative DNA damage in the presence of Fe2+
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MOLECULAR AND CELLULAR BIOCHEMISTRY (2001)
Oxidation of melatonin by oxoferryl hemoglobin: A mechanistic study
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FREE RADICAL RESEARCH (2001)
Biochemical reactivity of melatonin with reactive oxygen and nitrogen species - A review of the evidence
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Myeloperoxidase-catalyzed oxidation of melatonin by activated neutrophils
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Evidence of prooxidant and antioxidant action of melatonin on human liver cell line HepG2
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Scavenging effect of melatonin on hydroxyl radicals generated by alloxan
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JOURNAL OF PINEAL RESEARCH (2000)
Nitrosation of melatonin by nitric oxide and peroxynitrite
B Blanchard et al.
JOURNAL OF PINEAL RESEARCH (2000)
Melatonin protects against stress-induced gastric lesions by scavenging the hydroxyl radical
D Bandyopadhyay et al.
JOURNAL OF PINEAL RESEARCH (2000)
Antioxidative effects of melatonin in protection against cellular damage caused by ionizing radiation
M Karbownik et al.
PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE (2000)
Increased levels of oxidatively damaged DNA induced by chromium(III) and H2O2:: protection by melatonin and related molecules
WB Qi et al.
JOURNAL OF PINEAL RESEARCH (2000)
Protective effects of melatonin against oxidation of guanine bases in DNA and decreased microsomal membrane fluidity in rat liver induced by whole body ionizing radiation
M Karbownik et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2000)
Melatonin scavenges hydroxyl radical and protects isolated rat hearts from ischemic reperfusion injury
S Kaneko et al.
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Melatonin-induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo
M Martín et al.
JOURNAL OF PINEAL RESEARCH (2000)
Influence of melatonin on free radical-induced changes in rat pancreatic beta-cells in vitro
H Ebelt et al.
JOURNAL OF PINEAL RESEARCH (2000)
Evidence for melatonin synthesis in mouse and human bone marrow cells
A Conti et al.
JOURNAL OF PINEAL RESEARCH (2000)
An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease
MA Pappolla et al.
JOURNAL OF NEURAL TRANSMISSION (2000)
Protective effects of melatonin against ischemia-reperfusion injury in the isolated rat heart
C Lagneux et al.
LIFE SCIENCES (2000)
The effect of melatonin on in vitro fertilization and embryo development in mice
B Ishizuka et al.
JOURNAL OF PINEAL RESEARCH (2000)
Hydroxyl radical reaction with melatonin molecule: A computational study
P Stasica et al.
JOURNAL OF PINEAL RESEARCH (2000)