期刊
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
卷 15, 期 2, 页码 1538-1542出版社
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jnn.2015.8671
关键词
Hydroxyapatite; Fullerenol; Nanocomposite; Surface Analysis
类别
资金
- Ministry of Science, Republic of Serbia [III45005, III45004]
Fullerenols are polyhydroxylated, water soluble derivatives of fullerene C-60, with potential application in medicine as diagnostic agents, antioxidants or nano drug carriers. This paper describes synthesis and physical characterization of a new nanocomposite hydroxyapatite/fullerenol. Surface of the nanocomposite hydroxyapatite/fullerenol is inhomogeneous with the diameter of the particles in the range from 100 nm to 350 nm. The zeta potential of this nanocomposite is ten times lower when compared to hydroxyapatite. Surface phosphate groups of hydroxyapatite are prone to forming hydrogen bonds, when in close contact with hydroxyl groups, which could lead to formation of hydrogen bonds between hydroxyapatite and hydroxyl groups of fullerenol. The surface of hydroxyapatite particles (-2.5 mV) was modified by fullerenol particles, as confirmed by the obtained zeta potential value of the nanocomposite biomaterial hydroxyapatite/fullerenol (-25.0 mV).
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