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Platinum complexes of terpyridine: Interaction and reactivity with biomolecules

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COORDINATION CHEMISTRY REVIEWS
卷 253, 期 9-10, 页码 1495-1516

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ELSEVIER SCIENCE SA
DOI: 10.1016/j.ccr.2008.12.009

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Platinum complexes; Terdentate nitrogen ligands; Intercalation; DNA; Protein labeling

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Research on the coordination chemistry of Pt(II) terpyridine complexes spans more than 75 years, with significant recent work exploring the bioinorganic and medicinal chemistry of this diverse and versatile family of coordination Compounds. This paper reviews the research literature describing investigations of the interactions of Pt(II) terpyridine complexes with nucleic acids and proteins. (C) 2008 Elsevier B.V. All rights reserved.

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