期刊
CONTRAST MEDIA & MOLECULAR IMAGING
卷 10, 期 2, 页码 96-110出版社
WILEY-HINDAWI
DOI: 10.1002/cmmi.1615
关键词
boron; fluorine-18; radiolabelling; fluoroborates; BODIPY; PET
资金
- Daisy Appeal charity [DAhul0211]
Standard [F-18]fluorination methods to form carbon-fluorine bonds can have some limitations such as low yield and the requirement for harsh reaction conditions. Inorganic approaches include the formation of boron-[F-18]fluorine bonds and have the potential to give high specific activities at room temperature forming a bond that is stablein vivo. There is considerable potential in future applications, particularly in relation to multimodal imaging and the provision of rapid efficient labelling protocols. Copyright (c) 2014 John Wiley & Sons, Ltd.
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