期刊
CONTRACEPTION
卷 81, 期 3, 页码 226-231出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.contraception.2009.09.012
关键词
Heavy menstrual bleeding; Thermal balloon ablation; Levonorgestrel-releasing intrauterine system; Endometrium
Background: Use of the levonorgestrel-releasing intrauterine system (LNG-IUS) was compared with thermal balloon ablation (TBA) for the treatment of heavy menstrual bleeding (HMB). Study Design: A prospective randomized trial comparing the LNG-IUS (n=30 women) and TBA (n=28 women). Results: Hemoglobin levels increased (p<.001) and blood loss was reduced (p<.001) in both groups after I year of treatment. Menstrual bleeding was less in the LNG-IUS group compared to the TBA group at 6 and 12 months of treatment (p=.035 and p=.048, respectively). Intermenstrual bleeding was significantly less in the TBA group at 6 months compared to the LNG-IUS group (p=.044); however, there was no significant difference at 12 months (p=.129). No difference was found in psychological aspects between pre- and posttreatment variables in either of the groups (p=.537). Conclusions: Both the LNG-IUS and TBA appear to be effective in controlling HMB; however, posttreatment uterine bleeding patterns are different. (C) 2010 Elsevier Inc. All rights reserved.
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