期刊
CONNECTIVE TISSUE RESEARCH
卷 50, 期 2, 页码 132-138出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/03008200802585622
关键词
Matrix Metalloproteinases; Skin Ageing; Connective Tissue Degradation; Photoageing; Chronological Ageing; Extracellular Matrix
Matrix metalloproteinases are a family of ubiquitous endopeptidases playing a role in many different physiological and pathological processes in the skin. They are also involved in cutaneous ageing. This review summarizes the features and regulation of these enzymes and presents an overview of the molecular mechanisms of both intrinsic and extrinsic skin ageing presents. The role of matrix metalloproteinases in skin ageing is discussed in detail.
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