期刊
COMPUTERS IN BIOLOGY AND MEDICINE
卷 43, 期 9, 页码 1234-1240出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.compbiomed.2013.06.011
关键词
Lumbar spine; Intervertebral disc; Degeneration; Biomechanics; Finite element analysis
类别
资金
- National Agenda Project (NAP)
- Korea Research Council of Fundamental Science Technology [NAP-09-2/P-13-JC-LU01-C01]
The effects of intervertebral disc (IVD) degeneration on biomechanics of the lumbar spine were analyzed. Finite element models of the lumbar spine with various degrees of IVD degeneration at the L4-L5 functional spinal unit (FSU) were developed and validated. With progression of degeneration, intersegmental rotation at the degenerated FSU decreased in flexion-extension and left-right lateral bending, intradiscal pressure at the adjacent FSUs increased in flexion and lateral bending, and facet joint forces at the degenerated FSU increased in lateral bending and axial rotation. These results could provide fundamental information for understanding the mechanism of injuries caused by IVD degeneration. (C) 2013 Elsevier Ltd. All rights reserved.
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