期刊
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
卷 97, 期 2, 页码 130-140出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.cmpb.2009.06.005
关键词
Glucose-insulin system; Human endocrinology; Physiology; Delay differential equations (DDEs); Parametric estimation
This paper aims to present a mathematical model to describe the plasma glucose and insulin daily variations on normal and diabetic subjects. The proposed model consists of two delay differential equations (DDEs) where five adjustable parameters are used to characterize the respective dynamics and oscillation behavior of normal and diabetic subjects. Several clinical data tests demonstrate that the suggested model is practical to approach the daily-life glucose dynamics on normal, diabetic Type 1 and Type 2 subjects. Moreover, the corresponding parameters are fairly persuasive to identify the patients' conditions of physiological functions. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据